Where is 5 alpha reductase found?

Asked by: Stacey Carey

The conversion of testosterone to dihydrotestosterone is catalyzed by the enzyme 5α-reductase (5AR), which exists in 2 forms: Type 1 and Type 2, both of which are found in the prostate. Type 1 is produced primarily in liver and skin and is carried to the prostate via the systemic circulation.

Which hormone is secreted by Leydig cells?

Testosterone

Testosterone. Testosterone is secreted from the interstitial cells of Leydig, which are in large concentration in the testis in newborns and adult males after puberty.

Where are Sertoli cells found?

seminiferous tubules

Sertoli cells are present in the seminiferous tubules of the male gonads, the testes. They were first observed in 1865 by a young Italian physician Enrico Sertoli and named after him. Sertoli cells comprise one of the two types of cells in the germinal epithelium, the other being of spermatogonia lineage.

Which hormone acts on Leydig cells?

LH

In men, LH causes the Leydig cells of the testes to produce testosterone. In women, LH triggers the creation of steroid hormones from the ovaries [1].

What hormone stimulates Sertoli cells?

FSH

LH stimulates Leydig cell T production, and FSH stimulates in Sertoli cells, in synergy with T, the production of regulatory molecules and nutrients needed for the maintenance of spermatogenesis.

Which pituitary hormone regulates Sertoli cells?

follicle-stimulating hormone

Explanation: FSH or follicle-stimulating hormone is secreted by the anterior pituitary gland. It stimulates Sertoli cells to secrete certain factors, which are required for the spermiogenesis process, i.e. the formation of spermatozoa from spermatids.