What is the difference between legend and adequan?

Asked by: Pamela Hill

Adequan is incorporated directly into the cartilage where it helps with the compression capabilities of the joint. It has been shown to help heal and aid in the long term health of articular cartilage. Legend is pure Hyaluronic Acid that is utilized by the synovial cells that line the joint capsule.

Is Adequan or legend better?

Legend and Adequan

Many folks prefer Adequan over Legend because it costs less and is easier to administer. Adequan is polysulfated glycosaminoglycan (PSGAG), which is proven to have an anti-inflammatory effect in the body.

Is Legend an anti-inflammatory?

Legend (hyaluronate sodium) from Boehringer Ingelheim is a sterile injectable solution used to treat inflammation in your horse’s joint lining. Legend is pure hyaluronic acid, similar to the hyaluronic acid present in natural joint fluid.

What is the generic for Adequan?

Polysulfated glycosaminoglycan/PSGAG (brand names: Adequan®, Chondroprotec®) is an arthritis medication used to prevent joint degeneration and to protect the cartilage in the joint.

What is the best joint injection for horses?

Probably the most commonly used HA products are Hylartin-V, HyVisc, Legend or Hyalovet. All of these products are labeled for intraarticular use insuring purity and consistency with each individual manufacturer. MAP-5 is hyaluronic acid used in sperm extender and is not labeled for, but has been used in joint therapy.

How long does legend injection last?

Legend is used as an intravenous injection, as opposed to the IM injection with Adequan. This 4cc IV injection is administered once weekly, for four weeks, and then on a monthly basis.

What is legend drug for horses?

(hyaluronate sodium) LEGEND Injectable Solution is indicated in the treatment of joint dysfunction of the carpus or fetlock in horses due to non-infectious synovitis associated with equine osteoarthritis. A horse’s joints often need medical support in order to decrease the effects of equine osteoarthritis.

What are the side effects for Legend?

ADVERSE REACTIONS:

Following intravenous use: Occasional depression, lethargy, and fever. Following intra-articular use: lameness, joint effusion, joint or injection site swelling, and joint pain.

Is Pentosan better than Adequan?

More people are using Pentosan because Adequan has been sporadically unavailable for the past couple of years and has increased in price substantially. Many have also found the effects of either of these are quite similar but Pentosan is easier to get from multiple sources while most have to get Adequan thru their vet.

What are the side effects of Adequan?

Side Effects of Adequan Canine

• Stinging on injection site.
• Upset stomach.
• Vomiting.
• Diarrhea.
• Depression.
• Abnormal bleeding.

What is the best treatment for arthritis in horses?

Adequan® is the only FDA-approved, disease-modifying drug for the treatment of degenerative joint disease. It contains polysulfated glycosaminoglycan (PSGAG), which travels into injured joints and stimulates new cartilage production, while also relieving signs of arthritis. Adequan is available in both IM and IA form.

Is pentosan and Adequan the same?

Pentosan polysulfate is similar to polysulfated glycosaminoglycans (Adequan^®), except that it is derived from beechwood hemicellulose rather than an animal product.

Does Adequan really work?

For most dogs, the benefits of Adequan administration greatly outweigh the possible risks. Along with weight management, physical therapy, and medications to manage pain and inflammation, Adequan can improve your pet’s quality of life.

What is the new injection for dogs with arthritis?

LIBRELA – A unique new treatment for arthritis in dogs!

But now there is a new very specialised monoclonal antibody given as a monthly injection called LIBRELA – this targets the pain receptors in the nerve itself-nerve growth factor NGF.

Can you give too much Adequan?

Overdose of Polysulfated Glycosaminoglycan (Adequan) is rare but could cause: Joint Pain. Swelling. Lameness.

Does Adequan affect the liver?

Toxicology studies have found that when megadoses are administered, liver and kidney changes are observed. Even in moderately over-large doses, platelet numbers are reduced and blood clotting problems may result.

Is Adequan hard on kidneys?

Adequan should be used with caution in dogs with renal or hepatic impairment (i.e. kidney or liver disease). This is because the kidneys are primarily responsible for excreting Adequan (i.e. removing it from the body).

Is there a difference between Adequan canine and equine?

Except for the dosing regimen, no significant differences exist between equine and canine Adequan, according to Dr. Gary Kaufman, a veterinarian in Scottsdale, Arizona. Injections of Adequan i.a. go directly into the joint, while Adequan i.m. and Adequan Canine are injected into the muscle.

Can you give Adequan more than once a month?

Use Adequan^® Canine early, at the first clinical signs of OA before it progresses, and cartilage is irreversibly damaged. Administer twice weekly for up to 4 weeks (maximum of 8 injections) at approved dosage of 2 mg/lb body weight (0.02 mL/lb or 1 mL/50 lb) by intramuscular (IM) injection only.

How effective is gabapentin for dogs?

There are conflicting clinical reports about its efficacy when used for this purpose, although some studies report improvement in as many as 50% of dogs studied. In dogs, oral Gabapentin is well absorbed in the duodenum, with peak levels occurring approximately one to two hours after administration.

Where should Adequan be injected?

Adequan is given as an injection either in the muscle or under the skin (subcutaneously). The dose is tapered down from twice weekly initially, to once monthly.

How long has Adequan been around?

Adequan was developed by Luitpold Pharmaceuticals, a German company that entered the United States market in 1978. The drug was first used to treat joint pain in horses in 1984.

Does Adequan regrow cartilage?

Adequan slows cartilage destruction and promotes cartilage repair in dogs. Adequan improves the texture of joint fluid, contributing to increased joint comfort and mobility. Proper use of Adequan is associated with very few side effects.

Is Adequan glucosamine?

The drug Adequan is an injectable that contains polysulfated glycosaminoglycan (PSGAG) extracted from cow trachea. You may have heard about, or even taken, glucosamine tablets to support joint health. Adequan is a more effective injectable form than that supplement.

How much does Adequan cost for dogs?

How Much Does It Cost? One 5mL vial of Adequan costs $70.00 and contains five doses for Haley’s weight of 50 pounds. So each monthly dose will cost around $14.00 after the initial loading series of shots is completed.

How much Adequan do I need for a 60 pound dog?

The recommended dose of Adequan^® Canine is 2 mg/lb body weight (. 02 mL/lb, or 1 mL per 50 lb), by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections).