What is Agmatine used for?

Asked by: Sean Sanchez

Agmatine is a chemical found in bacteria, plants, and animals, including humans. It is made from the amino acid known as arginine. Agmatine is commonly used by mouth for depression, nerve pain, improving athletic performance, and many more conditions.

When should you take agmatine?

A daily dose of 2.67 g agmatine sulfate was encapsulated in gelatin capsules; the regimen consists of six capsules daily, each containing 445 mg, three in the morning and three in the evening after meals.

Does agmatine cause weight gain?

Influence on Body Weight Gain and Tissue Fat or Protein Mass. The consumption of AGM resulted in about a 15% reduction in body weight (BW) gain between 30 and 55 days in HFD + AGM or SD + AGM compared with the HFD or SD study group, respectively (Fig. 1d).

Does agmatine give you energy?

Agmatine, a supp taken for that very purpose, has been on scientists’ radar of late. And the drug pros have found it deserving of praise. The compound affects bodily functions that reduce fat stores, improve both mental and physical energy, fight disease and improve your sexual performance.

Is agmatine a drug?

Agmatine is both an experimental and investigational drug. As an investigational drug, it is being studied in a non-blinded prospective case study in the United States looking at patients who have been diagnosed with small fiber peripheral neuropathy between the ages of 18 to 75 years.

Is agmatine good for sleep?

I take this to help sleep. Specifically I’ll take one in the predawn hour when I nearly always wake up at least once, and it seems to help me get back to sleep very solidly for the last hour or two. It’s almost like it anchors me down in deep sleep and I wake up feeling like the sleep did its job better.

Is agmatine addictive?

Non-addictive: Blocks opioid tolerance and dependence. Reverses chronic pain: Decreases pain associated with inflammation and nerve injury. Permeates the blood-brain barrier and readily achieves a potent analgesic effect.

Does agmatine help anxiety?

Agmatine significantly enhanced locomotion in open filed test and decreased anxiety as observed in elevated plus maze test (p < 0.01).

Is agmatine safe?

Conclusions. Dietary agmatine sulfate is safe and efficacious treatment for alleviating pain and improving quality of life in lumbar disc-associated radiculopathy.

How fast does agmatine work for depression?

Agmatine (20 and 40mg/kg, i.p.) alone and in combination with NO modulators like L-NAME (15mg/kg, i.p.) and l-arginine (400mg/kg i.p.) were administered daily. The results showed that 4-weeks CUMS produces significant depression and anxiety-like behaviour.

Does agmatine increase dopamine?

In addition, agmatine treatment in control mice increased noradrenaline, serotonin, and dopamine levels, CREB phosphorylation, mature BDNF and synaptotagmin I immunocontents, and reduced pro-BDNF immunocontent in the hippocampus.

Is agmatine the same as arginine?

‘ Arginine, a BCAA, is thought to increase nitric oxide (nNOS and eNOS). Agmatine, on the other hand, decreases nNOS, and so the two do not play nice. By reducing the effectiveness of agmatine, arginine inhibits the neurological and physiological benefits you get from the chemical.